Key terms and Concepts

Pharmacokinetics: metabolic status, ability to metabolize certain drugs

Pharmacodynamics: ability to respond to a drug at the level of the drug target or receptor

Pharmacogenetics: genetic influence on both the pharmcokinetics and pharmcodynamics

Pharmacogenomics: examines inherited variations in genes that dictate drug response

Genomic screening is now available to detect low/medium/high metabolizers and polymorphisms associated with adverse side-effects of common analgesics

Epigenetic profiles could enhance ability to reach the right regimen more quickly

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